CPTAC DCC – Proteomics Data Coordinating Center

Background:

21st century medicine involves the integration of data from many sources as researchers and physicians address diseases, like cancer, in a comprehensive fashion.  In this project our team is focused on the cancer proteome and our challenge is to receive large volumes of mass spectrometry data from research groups in the Clinical Proteomic Tumor Analysis Consortium (CPTAC).  The proteomics data needs to be moved in a secure fashion, with no loss of content, and then these data must be made available to the public so that all researchers interested in the cancer proteome can access these data.

The proteomic data storage site previously used by the research community had problems with loss of data from files and slow times for data transfer.

Our Engagement:

  • ESAC, Inc. created a secure data portal for users by combining a web server with an Aspera, high-speed data transfer server.
  • Data is encrypted in transit and then verified by an md5 checksum
  • Daily transfer logs were developed to track and troubleshoot errors
  • The web site provides private areas for each research team to exchange data and also a shared area for the whole CPTAC program

Please visit the CPTAC Data Coordinating Center to know more about the Data Center and the Portal.

Outcome:

Establishment of a central repository for proteomic cancer data that provides rapid data upload from secure data generators, and subsequent distribution to the cancer community.

Other Projects:

ESAC continues to be an exceptional collaborator providing on-site contractors with both the expertise for building new tools and data integration platforms, and the subject matter expertise in the biosciences needed to manage projects and provide significant added value beyond the technology development.

Director
Innovation Center for Biomedical Informatics at Georgetown University Medical Center

ESAC's technical savvy and personable staff provides tremendous value to projects involving multi-center coordination and high dimensional data management. They merge a fundamental understanding of biology with expertise in data quality control and data security. Integrating all of these factors is key to delivering a secure and fast data portal for the scientific community.

Program Manager
NCI

We are quite impressed with not only by the technical skills provided by ESAC's software engineers but also by the depth and breadth of their subject matter experts who have provided guidance on standards and interoperability, quality assurance, and project management issues.

COTR
HHS/ONC

ESAC significantly improved the quality of bioinformatics applications of the NCI CBIIT program using industry best practices to ensure systems were validated both functionally and scientifically for use by the community.

Program Manager
NCI

Contact Us

Address

1801 Research Blvd.
Suite 500
Rockville, MD 20850
Location

Phone

(855) ESAC INC
(855) 372 2462

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