Background:
The Center for Biomedical Informatics and Information Technology (CBIIT) helps speed scientific discovery and facilitates translational research by building many types of tools and resources that enable information to be shared along the continuum from the scientific bench to the clinical bedside and back.
CBIIT offers critical open-source infrastructure components that others can use to develop valuable databases and software tools to meet specific research needs. CBIIT’s expanding suite of tools is built from these foundational components including:
- caArray – microarray data management system
- caIntegrator – web-based software package that allows researchers to set up custom web portals for integrative research
- National Biomedical Imaging Archive (NBIA) – searchable, national repository integrating in vivo cancer images with clinical and genomic data
Our Engagement:
ESAC, Inc. supported the mission of CBIIT by providing a team of Subject Matter Experts (SMEs) with extensive knowledge and experience in life sciences, bioinformatics and quality assurance. Our engagement at NCI included:
- Validated algorithms by reproducing the results manually and comparing with the system output.
- Researched and recommended the best methods for research based on latest bioinformatics literature and findings.
- Provided Subject Matter Expertise ensure that the correct methods and parameters are used for the scientific analysis.
- Curated clinical and genomic data for public availability through National Cancer Institute software tools.
- Presented software tools in live demonstrations and at scientific meetings.
- Performed manual and automated tests
- Find, report, and track defects in software
Outcome:
Using industry best practices in Quality Assurance techniques, ESAC, Inc. has been able to provide an exponential increase in the quality and scientific validity of NCICB’s bioinformatics applications. Our Subject Matter Experts were able to provide scientific validation of the systems and databases including validation of algorithms, validation with latest bioinformatics literatures and appropriate methods were used for scientific analysis.
Other Projects: