Proteomic Data Commons (PDC)

Background:

Currently, the researchers’ ability to access diverse datasets, and perform robust and reproducible analyses is stifled by the siloed nature of the current informatics infrastructure.  As a part of the NCI’s cancer research data ecosystem, the aim of PDC is to overcome this challenge by making it possible for any researcher to ask new and fundamental questions about cancer and provide much-needed tools to accelerate research and the development of personalized treatments for individual patients.  Cancer researchers can now easily access the multi-omics (proteomic, genomic, imaging, etc.) data from many sources across the CRDC’s virtual, expandable infrastructure, thus lowering the entry barrier for anyone who wants to get involved in integrative research.

Our Engagement:

  • Provide a secure, accessible, cloud-hosted environment
  • Scalable to accommodate large volumes of data.
  • Compute power for data analysis
  • Interoperate with other NCI analytical platforms
  • Build an extensible data model and harmonization standards

Outcome:

The PDC is a next-generation proteomic data repository that aims to make biomedical data sets accessible and connected at an unprecedented scale to facilitate creative new ways to combine, analyze, and ask questions that drive precision medicine. Hosted on the Amazon Web Services (AWS) cloud platform, the PDC provides access to highly curated and standardized biospecimen, clinical, and proteomic data through an intuitive interface to filter, query, search, visualize and download the data and metadata. In addition, there are robust APIs available for bioinformaticians to access the data programmatically for analysis with cloud-native and cloud-agnostic applications alike. What this means is that PDC users can access the data from anywhere in the world to obtain the data they need quickly, easily, and securely.

Other Projects:

We are quite impressed with not only by the technical skills provided by ESAC's software engineers but also by the depth and breadth of their subject matter experts who have provided guidance on standards and interoperability, quality assurance, and project management issues.

COTR
HHS/ONC

ESAC continues to be an exceptional collaborator providing on-site contractors with both the expertise for building new tools and data integration platforms, and the subject matter expertise in the biosciences needed to manage projects and provide significant added value beyond the technology development.

Director
Innovation Center for Biomedical Informatics at Georgetown University Medical Center

ESAC significantly improved the quality of bioinformatics applications of the NCI CBIIT program using industry best practices to ensure systems were validated both functionally and scientifically for use by the community.

Program Manager
NCI

ESAC's technical savvy and personable staff provides tremendous value to projects involving multi-center coordination and high dimensional data management. They merge a fundamental understanding of biology with expertise in data quality control and data security. Integrating all of these factors is key to delivering a secure and fast data portal for the scientific community.

Program Manager
NCI

Contact Us

Address

1801 Research Blvd.
Suite 500
Rockville, MD 20850
Location

Phone

(855) ESAC INC
(855) 372 2462

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